STK4 regulates TLR pathways and protects against chronic inflammation-related hepatocellular carcinoma.
Li W, Xiao J, Zhou X, Xu M, Hu C, Xu X, Lu Y, Liu C, Xue S, Nie L, Zhang H, Li Z, Zhang Y, Ji F, Hui L, Tao W, Wei B, Wang H.
Li W, et al.
J Clin Invest. 2015 Nov 2;125(11):4239-54. doi: 10.1172/JCI81203. Epub 2015 Oct 12.
J Clin Invest. 2015.
PMID: 26457732
Free PMC article.
Moreover, serum STK4 levels were specifically decreased in HCC patients with high levels of IL-6. ...Together, our results suggest that STK4 has potential as a diagnostic biomarker and therapeutic target for inflammation-induced HCC....
Moreover, serum STK4 levels were specifically decreased in HCC patients with high levels of IL-6. ...Together, our results suggest th …